Activation of Engineered Protein Tyrosine Phosphatases with the Biarsenical Compound AsCy3-EDT<sub>2</sub>.

Chan, Wai Cheung; Knowlton, Gregory S; Bishop, Anthony C

Activation of Engineered Protein Tyrosine Phosphatases with the Biarsenical Compound AsCy3-EDT₂.

Chan, Wai Cheung; Knowlton, Gregory S; Bishop, Anthony C.

Afiliação

Chan WC; Amherst College, Department of Chemistry, Amherst, MA, 01002, USA.
Knowlton GS; Amherst College, Department of Chemistry, Amherst, MA, 01002, USA.
Bishop AC; Amherst College, Department of Chemistry, Amherst, MA, 01002, USA.

Chembiochem ; 18(19): 1950-1958, 2017 10 05.

Article em En | MEDLINE | ID: mdl-28745017

Assuntos

Arsenicais/farmacologia; Engenharia de Proteínas; Proteínas Tirosina Fosfatases/metabolismo; Arsenicais/química; Relação Dose-Resposta a Droga; Modelos Moleculares; Estrutura Molecular; Proteínas Tirosina Fosfatases/química; Proteínas Tirosina Fosfatases/genética; Fatores de Tempo

Palavras-chave

AsCy3; enzyme activation; enzymes; protein engineering; protein tyrosine phosphatases

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arsenicais / Engenharia de Proteínas / Proteínas Tirosina Fosfatases Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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