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Dynamic and accurate assessment of acetaminophen-induced hepatotoxicity by integrated photoacoustic imaging and mechanistic biomarkers in vivo.
Brillant, Nathalie; Elmasry, Mohamed; Burton, Neal C; Rodriguez, Josep Monne; Sharkey, Jack W; Fenwick, Stephen; Poptani, Harish; Kitteringham, Neil R; Goldring, Christopher E; Kipar, Anja; Park, B Kevin; Antoine, Daniel J.
Afiliação
  • Brillant N; Department of Molecular & Clinical Pharmacology, MRC Centre for Drug Safety Science, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Elmasry M; Department of Molecular & Clinical Pharmacology, MRC Centre for Drug Safety Science, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Burton NC; iThera Medical, Munich, Germany.
  • Rodriguez JM; Department of Veterinary Pathology, Institute of Veterinary Science, University of Liverpool, Liverpool, UK.
  • Sharkey JW; Department of Cellular & Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Fenwick S; General Surgery, Aintree University Hospital, Liverpool, Merseyside, UK.
  • Poptani H; Department of Cellular & Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Kitteringham NR; Department of Molecular & Clinical Pharmacology, MRC Centre for Drug Safety Science, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Goldring CE; Department of Molecular & Clinical Pharmacology, MRC Centre for Drug Safety Science, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Kipar A; Institute of Global Health, University of Liverpool, Liverpool, UK; Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
  • Park BK; Department of Molecular & Clinical Pharmacology, MRC Centre for Drug Safety Science, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Antoine DJ; Department of Molecular & Clinical Pharmacology, MRC Centre for Drug Safety Science, Institute of Translational Medicine, University of Liverpool, Liverpool, UK. Electronic address: d.antoine@liverpool.ac.uk.
Toxicol Appl Pharmacol ; 332: 64-74, 2017 10 01.
Article em En | MEDLINE | ID: mdl-28755860

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Hepática Induzida por Substâncias e Drogas / Técnicas Fotoacústicas / Fígado / Acetaminofen Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença Hepática Induzida por Substâncias e Drogas / Técnicas Fotoacústicas / Fígado / Acetaminofen Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article