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Mobile phone radiofrequency exposure has no effect on DNA double strand breaks (DSB) in human lymphocytes.
Danese, Elisa; Lippi, Giuseppe; Buonocore, Ruggero; Benati, Marco; Bovo, Chiara; Bonaguri, Chiara; Salvagno, Gian Luca; Brocco, Giorgio; Roggenbuck, Dirk; Montagnana, Martina.
Afiliação
  • Danese E; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
  • Lippi G; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
  • Buonocore R; Laboratory of Clinical Chemistry and Haematology, Academic Hospital of Parma, Parma, Italy.
  • Benati M; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
  • Bovo C; Medical Direction, University Hospital of Verona, Verona, Italy.
  • Bonaguri C; Laboratory of Clinical Chemistry and Haematology, Academic Hospital of Parma, Parma, Italy.
  • Salvagno GL; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
  • Brocco G; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
  • Roggenbuck D; Faculty of Natural Sciences, Brandenburg Technical University, Senftenberg, Germany and Medipan GmbH, Dahlewitz/Berlin, Germany.
  • Montagnana M; Section of Clinical Biochemistry, University of Verona, Verona, Italy.
Ann Transl Med ; 5(13): 272, 2017 Jul.
Article em En | MEDLINE | ID: mdl-28758098
ABSTRACT

BACKGROUND:

The use of mobile phones has been associated with an increased risk of developing certain type of cancer, especially in long term users. Therefore, this study was aimed to investigate the potential genotoxic effect of mobile phone radiofrequency exposure on human peripheral blood mononuclear cells in vitro.

METHODS:

The study population consisted in 14 healthy volunteers. After collection of two whole blood samples, the former was placed in a plastic rack, 1 cm from the chassis of a commercial mobile phone (900 MHz carrier frequency), which was activated by a 30-min call. The second blood sample was instead maintained far from mobile phones or other RF sources. The influence of mobile phone RF on DNA integrity was assessed by analyzing γ-H2AX foci in lymphocytes using immunofluorescence staining kit on AKLIDES.

RESULTS:

No measure of γ-H2AX foci was significantly influenced by mobile phone RF exposure, nor mobile phone exposure was associated with significant risk of genetic damages in vitro (odds ratio comprised between 0.27 and 1.00).

CONCLUSIONS:

The results of this experimental study demonstrate that exposure of human lymphocytes to a conventional 900 MHz RF emitted by a commercial mobile phone for 30 min does not significantly impact DNA integrity.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article