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Assessment of the Target Engagement and D-Serine Biomarker Profiles of the D-Amino Acid Oxidase Inhibitors Sodium Benzoate and PGM030756.
Howley, Eimear; Bestwick, Michael; Fradley, Rosa; Harrison, Helen; Leveridge, Mathew; Okada, Kengo; Fieldhouse, Charlotte; Farnaby, Will; Canning, Hannah; Sykes, Andy P; Merchant, Kevin; Hazel, Katherine; Kerr, Catrina; Kinsella, Natasha; Walsh, Louise; Livermore, David G; Hoffman, Isaac; Ellery, Jonathan; Mitchell, Phillip; Patel, Toshal; Carlton, Mark; Barnes, Matt; Miller, David J.
Afiliação
  • Howley E; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Bestwick M; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Fradley R; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK. rosa_fradley@hotmail.co.uk.
  • Harrison H; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Leveridge M; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Okada K; Biomolecular Research Laboratories, Shonan Research Center, Takeda Pharmaceutical Company Ltd, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 25108555, Japan.
  • Fieldhouse C; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Farnaby W; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Canning H; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Sykes AP; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Merchant K; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Hazel K; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Kerr C; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Kinsella N; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Walsh L; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Livermore DG; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Hoffman I; Takeda California Inc., 10410 Science Center Dr, San Diego, CA, 92121, USA.
  • Ellery J; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Mitchell P; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Patel T; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Carlton M; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Barnes M; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
  • Miller DJ; Takeda Cambridge Ltd, 418 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire, CB4 0PA, UK.
Neurochem Res ; 42(11): 3279-3288, 2017 Nov.
Article em En | MEDLINE | ID: mdl-28780732
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridazinas / Serina / Cerebelo / Clorobenzenos / Benzoato de Sódio / D-Aminoácido Oxidase / Inibidores Enzimáticos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridazinas / Serina / Cerebelo / Clorobenzenos / Benzoato de Sódio / D-Aminoácido Oxidase / Inibidores Enzimáticos Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article