The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability.

Edelblum, Karen L; Sharon, Gil; Singh, Gurminder; Odenwald, Matthew A; Sailer, Anne; Cao, Severine; Ravens, Sarina; Thomsen, Irene; El Bissati, Kamal; McLeod, Rima; Dong, Chen; Gurbuxani, Sandeep; Prinz, Immo; Mazmanian, Sarkis K; Turner, Jerrold R

The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability.

Edelblum, Karen L; Sharon, Gil; Singh, Gurminder; Odenwald, Matthew A; Sailer, Anne; Cao, Severine; Ravens, Sarina; Thomsen, Irene; El Bissati, Kamal; McLeod, Rima; Dong, Chen; Gurbuxani, Sandeep; Prinz, Immo; Mazmanian, Sarkis K; Turner, Jerrold R.

Afiliação

Edelblum KL; Department of Pathology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.
Sharon G; Department of Pathology, University of Chicago, Chicago, Illinois.
Singh G; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California.
Odenwald MA; Department of Pathology, University of Chicago, Chicago, Illinois.
Sailer A; Departments of Pathology and Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Cao S; Department of Pathology, University of Chicago, Chicago, Illinois.
Ravens S; Department of Pathology, University of Chicago, Chicago, Illinois.
Thomsen I; Department of Pathology, University of Chicago, Chicago, Illinois.
El Bissati K; Institute of Immunology, Hannover Medical School, Hannover, Germany.
McLeod R; Institute of Immunology, Hannover Medical School, Hannover, Germany.
Dong C; Department of Ophthalmology and Visual Sciences, University of Chicago, Chicago, Illinois.
Gurbuxani S; Department of Pediatrics, University of Chicago, Chicago, Illinois.
Prinz I; Department of Ophthalmology and Visual Sciences, University of Chicago, Chicago, Illinois.
Mazmanian SK; Department of Pediatrics, University of Chicago, Chicago, Illinois.
Turner JR; Institute for Immunology, Tsinghua University, Beijing, China.

Cell Mol Gastroenterol Hepatol ; 4(2): 285-297, 2017 Sep.

Article em En | MEDLINE | ID: mdl-28795125

Palavras-chave

Barrier Function; CA-MLCK, constitutively active myosin light chain kinase; CD4 T Cell; CFU, colony-forming unit; GF, germ-free; IL, interleukin; Ig, immunoglobulin; LP, lamina propria; Microbiota; Mucosal Immunity; SEM, standard error of the mean; SFB, segmented filamentous bacteria; SPF, specific pathogenfree; Salmonella; Tight Junction; WT, wild-type

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article