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The novel resveratrol derivative 3,5-diethoxy-3',4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro.
Park, Jae-Woo; Choi, Woo-Gyun; Lee, Phil-Jun; Chung, Su-Wol; Kim, Byung-Sam; Chung, Hun-Taeg; Cho, Sungchan; Kim, Jong-Heon; Kang, Byoung-Heon; Kim, Hyoungsu; Kim, Hong-Pyo; Back, Sung-Hoon.
Afiliação
  • Park JW; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
  • Choi WG; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
  • Lee PJ; School of Pharmacy, Ajou University, Suwon 16499, Korea.
  • Chung SW; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
  • Kim BS; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
  • Chung HT; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
  • Cho S; Targeted Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongwon, Chungbuk 28116, and Department of Biomolecular Science, University of Science and Technology, Daejeon 34554, Korea.
  • Kim JH; Cancer Cell and Molecular Biology Branch, Research Institute, and Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Korea.
  • Kang BH; School of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan 44919, Korea.
  • Kim H; School of Pharmacy, Ajou University, Suwon 16499, Korea.
  • Kim HP; School of Pharmacy, Ajou University, Suwon 16499, Korea.
  • Back SH; School of Biological Sciences, University of Ulsan, Ulsan 44610, Korea.
Acta Pharmacol Sin ; 38(11): 1486-1500, 2017 Nov.
Article em En | MEDLINE | ID: mdl-28795692
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Espécies Reativas de Oxigênio / Carcinoma Hepatocelular / Estresse Oxidativo / Estresse do Retículo Endoplasmático / Neoplasias Hepáticas / Mitocôndrias / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Espécies Reativas de Oxigênio / Carcinoma Hepatocelular / Estresse Oxidativo / Estresse do Retículo Endoplasmático / Neoplasias Hepáticas / Mitocôndrias / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article