Cerebral Oxidative Stress and Microvasculature Defects in TNF-&#945; Expressing Transgenic and Porphyromonas gingivalis-Infected ApoE-/- Mice.

Rokad, Farheen; Moseley, Ryan; Hardy, Rowan S; Chukkapalli, Sasanka; Crean, StJohn; Kesavalu, Lakshmyya; Singhrao, Sim K

Cerebral Oxidative Stress and Microvasculature Defects in TNF-α Expressing Transgenic and Porphyromonas gingivalis-Infected ApoE-/- Mice.

Rokad, Farheen; Moseley, Ryan; Hardy, Rowan S; Chukkapalli, Sasanka; Crean, StJohn; Kesavalu, Lakshmyya; Singhrao, Sim K.

Afiliação

Rokad F; Dementia and Neurodegenerative Diseases Research Group, Faculty of Clinical and Biomedical Sciences, School of Dentistry, University of Central Lancashire, Preston, UK.
Moseley R; Stem Cells, Wound Repair and Regeneration, School of Dentistry, Cardiff University, Cardiff, UK.
Hardy RS; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
Chukkapalli S; Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Crean S; Dementia and Neurodegenerative Diseases Research Group, Faculty of Clinical and Biomedical Sciences, School of Dentistry, University of Central Lancashire, Preston, UK.
Kesavalu L; Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL, USA.
Singhrao SK; Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, USA.

J Alzheimers Dis ; 60(2): 359-369, 2017.

Article em En | MEDLINE | ID: mdl-28800332

Assuntos

Apolipoproteínas E/deficiência; Infecções por Bacteroidaceae/fisiopatologia; Microvasos/patologia; Estresse Oxidativo/genética; Porphyromonas gingivalis/patogenicidade; Fator de Necrose Tumoral alfa/metabolismo; Animais; Apolipoproteínas E/genética; Infecções por Bacteroidaceae/genética; Infecções por Bacteroidaceae/virologia; Modelos Animais de Doenças; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Microvasos/virologia; Fenil-Hidrazinas/metabolismo; Carbonilação Proteica/genética; Carbonilação Proteica/fisiologia; Fator de Necrose Tumoral alfa/genética

Palavras-chave

Hippocampus; Porphyromonas gingivalis; infection; microvasculature; oxidative stress/damage; tight junction proteins

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apolipoproteínas E / Fator de Necrose Tumoral alfa / Infecções por Bacteroidaceae / Porphyromonas gingivalis / Estresse Oxidativo / Microvasos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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