Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228).

Lévi, Francis; Karaboué, Abdoulaye; Saffroy, Raphaël; Desterke, Christophe; Boige, Valerie; Smith, Denis; Hebbar, Mohamed; Innominato, Pasquale; Taieb, Julien; Carvalho, Carlos; Guimbaud, Rosine; Focan, Christian; Bouchahda, Mohamed; Adam, René; Ducreux, Michel; Milano, Gérard; Lemoine, Antoinette

Lévi, Francis; Karaboué, Abdoulaye; Saffroy, Raphaël; Desterke, Christophe; Boige, Valerie; Smith, Denis; Hebbar, Mohamed; Innominato, Pasquale; Taieb, Julien; Carvalho, Carlos; Guimbaud, Rosine; Focan, Christian; Bouchahda, Mohamed; Adam, René; Ducreux, Michel; Milano, Gérard; Lemoine, Antoinette.

Afiliação

Lévi F; INSERM, UMRS 935 Team 'Cancer Chronotherapy and Postoperative Liver Function', Campus CNRS, 7 rue Guy Môquet, and UMRS 1193 'Physiopathology and treatment of Liver diseases', Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Karaboué A; Université Paris Sud, UFR médecine, Institut André Lwoff, Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Saffroy R; Assistance Publique-Hopitaux de Paris, Paul Brousse Hospital, Departments of Medical Oncology, Biochemistry and Oncogenetics, and Hepatobiliary Center, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Desterke C; Cancer Chronotherapy Unit, Warwick Medical School, Warwick University, Gibbet Hill Road, Coventry CV4 7AL, UK.
Boige V; INSERM, UMRS 935 Team 'Cancer Chronotherapy and Postoperative Liver Function', Campus CNRS, 7 rue Guy Môquet, and UMRS 1193 'Physiopathology and treatment of Liver diseases', Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Smith D; AK-SCIENCE, Research and Therapeutic Innovation, 34 Boulevard de Stalingrad, 94400 Vitry-Sur-Seine, France.
Hebbar M; INSERM, UMRS 935 Team 'Cancer Chronotherapy and Postoperative Liver Function', Campus CNRS, 7 rue Guy Môquet, and UMRS 1193 'Physiopathology and treatment of Liver diseases', Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Innominato P; Université Paris Sud, UFR médecine, Institut André Lwoff, Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Taieb J; Assistance Publique-Hopitaux de Paris, Paul Brousse Hospital, Departments of Medical Oncology, Biochemistry and Oncogenetics, and Hepatobiliary Center, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Carvalho C; INSERM, UMRS 935 Team 'Cancer Chronotherapy and Postoperative Liver Function', Campus CNRS, 7 rue Guy Môquet, and UMRS 1193 'Physiopathology and treatment of Liver diseases', Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Guimbaud R; Université Paris Sud, UFR médecine, Institut André Lwoff, Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Focan C; Gustave-Roussy Institute, 114 Rue Edouard Vaillant, 94400 Villejuif, France.
Bouchahda M; Saint André Hospital, 1 Rue Jean Burguet, 33000 Bordeaux, France.
Adam R; Medical Oncology Unit, Huriez Hospital, 1 rue Polonovski, 59037 Lille, France.
Ducreux M; INSERM, UMRS 935 Team 'Cancer Chronotherapy and Postoperative Liver Function', Campus CNRS, 7 rue Guy Môquet, and UMRS 1193 'Physiopathology and treatment of Liver diseases', Paul Brousse Hospital, 14 avenue Paul-Vaillant-Couturier, 94800 Villejuif, France.
Milano G; Cancer Chronotherapy Unit, Warwick Medical School, Warwick University, Gibbet Hill Road, Coventry CV4 7AL, UK.
Lemoine A; Georges Pompidou European Hospital, 20 Rue Leblanc, 75015 Paris, France.

Br J Cancer ; 117(7): 965-973, 2017 Sep 26.

Article em En | MEDLINE | ID: mdl-28817838

Assuntos

Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem; Arilamina N-Acetiltransferase/genética; Neoplasias Colorretais/genética; Neoplasias Hepáticas/tratamento farmacológico; Neoplasias Hepáticas/genética; Vitamina K Epóxido Redutases/genética; Subfamília B de Transportador de Cassetes de Ligação de ATP/genética; Administração Intravenosa; Adulto; Idoso; Protocolos de Quimioterapia Combinada Antineoplásica/efeitos adversos; Camptotecina/administração & dosagem; Camptotecina/análogos & derivados; Proteínas da Membrana Plasmática de Transporte de Catecolaminas/genética; Cetuximab/administração & dosagem; Neoplasias Colorretais/patologia; Citocromo P-450 CYP2C19/genética; Citocromo P-450 CYP2C9/genética; Diarreia/induzido quimicamente; Diarreia/genética; Intervalo Livre de Doença; Feminino; Fluoruracila/administração & dosagem; Glucuronosiltransferase/genética; Hepatectomia; Artéria Hepática; Humanos; Infusões Intra-Arteriais; Irinotecano; Neoplasias Hepáticas/secundário; Neoplasias Hepáticas/cirurgia; Masculino; Pessoa de Meia-Idade; Neutropenia/induzido quimicamente; Neutropenia/genética; Compostos Organoplatínicos/administração & dosagem; Oxaliplatina; Farmacogenética; Polimorfismo de Nucleotídeo Único; Taxa de Sobrevida; Resultado do Tratamento

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arilamina N-Acetiltransferase / Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Vitamina K Epóxido Redutases / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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