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Rethinking Schistosomiasis Vaccine Development: Synthetic Vesicles.
Egesa, Moses; Hoffmann, Karl F; Hokke, Cornelis H; Yazdanbakhsh, Maria; Cose, Stephen.
Afiliação
  • Egesa M; Department of Medical Microbiology, School of Biomedical Sciences, Makerere University College of Health Sciences, Kampala, Uganda; Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS, Entebbe, Uganda.
  • Hoffmann KF; Institute of Biological, Environmental and Rural Sciences (IBERS), Edward Llwyd Building, Room 3-31, Aberystwyth University, Ceredigion, SY23 3DA, UK.
  • Hokke CH; Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
  • Yazdanbakhsh M; Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
  • Cose S; Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS, Entebbe, Uganda; Department of Clinical Research, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK. Electronic address: stephen.cose@lshtm.ac.uk.
Trends Parasitol ; 33(12): 918-921, 2017 12.
Article em En | MEDLINE | ID: mdl-28818406
There is currently no vaccine against schistosomiasis. With few Schistosoma vaccine candidates in clinical trials, unexplored antigens from the vulnerable schistosomulum should be considered as possible vaccine candidates. In addition, we suggest developing synthetic vesicles as a new delivery vehicle and adjuvant for immunoprophylactic schistosomula vaccine candidates.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquistossomose / Vacinas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquistossomose / Vacinas Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article