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Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.
Pancera, Marie; Lai, Yen-Ting; Bylund, Tatsiana; Druz, Aliaksandr; Narpala, Sandeep; O'Dell, Sijy; Schön, Arne; Bailer, Robert T; Chuang, Gwo-Yu; Geng, Hui; Louder, Mark K; Rawi, Reda; Soumana, Djade I; Finzi, Andrés; Herschhorn, Alon; Madani, Navid; Sodroski, Joseph; Freire, Ernesto; Langley, David R; Mascola, John R; McDermott, Adrian B; Kwong, Peter D.
Afiliação
  • Pancera M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Lai YT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Bylund T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Druz A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Narpala S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Schön A; Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA.
  • Bailer RT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Chuang GY; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Geng H; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Louder MK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Rawi R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Soumana DI; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Finzi A; Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, Quebec, Canada.
  • Herschhorn A; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Madani N; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Sodroski J; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Freire E; Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA.
  • Langley DR; Computer Assisted Drug Design, Bristol-Myers Squibb, Research and Development, Wallingford, Connecticut, USA.
  • Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • McDermott AB; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Nat Chem Biol ; 13(10): 1115-1122, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28825711

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Triazóis / Proteína gp41 do Envelope de HIV / Proteína gp120 do Envelope de HIV / Internalização do Vírus / Bibliotecas de Moléculas Pequenas Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Triazóis / Proteína gp41 do Envelope de HIV / Proteína gp120 do Envelope de HIV / Internalização do Vírus / Bibliotecas de Moléculas Pequenas Idioma: En Ano de publicação: 2017 Tipo de documento: Article