Soluble Extracellular Domain of Death Receptor 5 Inhibits TRAIL-Induced Apoptosis by Disrupting Receptor-Receptor Interactions.

Vunnam, Nagamani; Lo, Chih Hung; Grant, Benjamin D; Thomas, David D; Sachs, Jonathan N

Vunnam, Nagamani; Lo, Chih Hung; Grant, Benjamin D; Thomas, David D; Sachs, Jonathan N.

Afiliação

Vunnam N; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, United States.
Lo CH; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, United States.
Grant BD; Fluorescence Innovations Inc., Minneapolis, MN 55455, United States.
Thomas DD; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, United States; Photonic Pharma LLC, Minneapolis, MN 55410, United States.
Sachs JN; Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, United States. Electronic address: jnsachs@umn.edu.

J Mol Biol ; 429(19): 2943-2953, 2017 09 15.

Article em En | MEDLINE | ID: mdl-28834692

Assuntos

Apoptose; Receptores do Ligante Indutor de Apoptose Relacionado a TNF/metabolismo; Ligante Indutor de Apoptose Relacionado a TNF/metabolismo; Linhagem Celular; Sobrevivência Celular; Análise Mutacional de DNA; Transferência Ressonante de Energia de Fluorescência; Humanos; Receptores do Ligante Indutor de Apoptose Relacionado a TNF/genética; Transdução de Sinais; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

TNF-related apoptosis inducing ligand; death receptor 5; pre-ligand assembly domain; time-resolved FRET; tumor necrosis factor receptors

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Ligante Indutor de Apoptose Relacionado a TNF / Receptores do Ligante Indutor de Apoptose Relacionado a TNF Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google