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Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
Torrents de la Peña, Alba; Julien, Jean-Philippe; de Taeye, Steven W; Garces, Fernando; Guttman, Miklos; Ozorowski, Gabriel; Pritchard, Laura K; Behrens, Anna-Janina; Go, Eden P; Burger, Judith A; Schermer, Edith E; Sliepen, Kwinten; Ketas, Thomas J; Pugach, Pavel; Yasmeen, Anila; Cottrell, Christopher A; Torres, Jonathan L; Vavourakis, Charlotte D; van Gils, Marit J; LaBranche, Celia; Montefiori, David C; Desaire, Heather; Crispin, Max; Klasse, Per Johan; Lee, Kelly K; Moore, John P; Ward, Andrew B; Wilson, Ian A; Sanders, Rogier W.
Afiliação
  • Torrents de la Peña A; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands.
  • Julien JP; Department of Integrative Structural and Computational Biology, Scripps CHAVI-ID, IAVI Neutralizing Antibody Center and Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
  • de Taeye SW; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands.
  • Garces F; Department of Integrative Structural and Computational Biology, Scripps CHAVI-ID, IAVI Neutralizing Antibody Center and Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Guttman M; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
  • Ozorowski G; Department of Integrative Structural and Computational Biology, Scripps CHAVI-ID, IAVI Neutralizing Antibody Center and Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Pritchard LK; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Behrens AJ; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Go EP; Department of Chemistry, University of Kansas, Lawrence, KS 66047, USA.
  • Burger JA; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands.
  • Schermer EE; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands.
  • Sliepen K; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands.
  • Ketas TJ; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA.
  • Pugach P; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA.
  • Yasmeen A; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA.
  • Cottrell CA; Department of Integrative Structural and Computational Biology, Scripps CHAVI-ID, IAVI Neutralizing Antibody Center and Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Torres JL; Department of Integrative Structural and Computational Biology, Scripps CHAVI-ID, IAVI Neutralizing Antibody Center and Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Vavourakis CD; Microbial Systems Ecology, Department of Freshwater and Marine Ecology, Institute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam 1098 XH, the Netherlands.
  • van Gils MJ; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands.
  • LaBranche C; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
  • Montefiori DC; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
  • Desaire H; Department of Chemistry, University of Kansas, Lawrence, KS 66047, USA.
  • Crispin M; Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Klasse PJ; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA.
  • Lee KK; Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.
  • Moore JP; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA.
  • Ward AB; Department of Integrative Structural and Computational Biology, Scripps CHAVI-ID, IAVI Neutralizing Antibody Center and Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Wilson IA; Department of Integrative Structural and Computational Biology, Scripps CHAVI-ID, IAVI Neutralizing Antibody Center and Collaboration for AIDS Vaccine Discovery (CAVD), The Scripps Research Institute, La Jolla, CA 92037, USA; The Skaggs Institute for Chemical Biology, The Scripps Research Institute,
  • Sanders RW; Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam 1105 AZ, the Netherlands; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA. Electronic address: rws2002@med.cornell.edu.
Cell Rep ; 20(8): 1805-1817, 2017 Aug 22.
Article em En | MEDLINE | ID: mdl-28834745
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: HIV-1 / Produtos do Gene env do Vírus da Imunodeficiência Humana Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article