Transcriptional induction of cellular gene expression during lytic infection with herpes simplex virus.
Biosci Rep
; 6(11): 945-51, 1986 Nov.
Article
em En
| MEDLINE
| ID: mdl-2883998
Herpes simplex virus Type 2 causes a severe repression of host cell biosynthesis at a number of levels. We show that despite this, non-viral cDNA clones derived from cellular RNA species which accumulate to high levels after infection can be isolated using differential screening techniques. By using nuclear run-off assays, we have shown that this RNA accumulation is mediated by transcriptional induction of the corresponding cellular genes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poli A
/
Transcrição Gênica
/
RNA Mensageiro
/
Regulação da Expressão Gênica
/
Simplexvirus
Limite:
Animals
Idioma:
En
Ano de publicação:
1986
Tipo de documento:
Article