[Simultaneous determination of eight hydroxyl naphthoquinones in different parts of Arnebiae euchroma by HPLC].
Zhongguo Zhong Yao Za Zhi
; 42(13): 2532-2537, 2017 Jul.
Article
em Zh
| MEDLINE
| ID: mdl-28840695
ABSTRACT
This present study is to develop an HPLC method for simultaneous determination of eight hydroxyl naphthoquinones, shikonin, ß-hydroxy-isovalerylshikonin, acetylshikonin, ß-acetoxy-isovalerylshikonin, deoxyshikonin, isobutyrylshikonin, ß,ß'-dimethylacrylshikonin and isovalerylshikonin. The eight constituents were measured on a Waters Xbridge C18 column (4.6 mm×250 mmï¼5 µm) with isocratic elution of acetonitrile-0.05% formic acid solution (70â¶30) at a flow rate of 1.0 mLâ¢min⻹. The detection wavelength was 275 nm and the column temperature was 30 â. The results of content determination indicated that significant differences of the eight compounds exist in every part of Arnebia euchromaï¼in which the highest part was the root bark, followed with the root, then the stem residues. The content of the xylem of root and aerial part was lower than the above parts. The results provided scientific basis for the medicinal parts of A. euchroma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Naftoquinonas
/
Boraginaceae
Idioma:
Zh
Ano de publicação:
2017
Tipo de documento:
Article