[Prenatal exposure to ambient air pollution and congenital heart disease: a Meta-analysis].
Zhonghua Liu Xing Bing Xue Za Zhi
; 38(8): 1121-1126, 2017 Aug 10.
Article
em Zh
| MEDLINE
| ID: mdl-28847067
ABSTRACT
Objective:
To explore the association between exposure to ambient air pollution during pregnancy and congenital heart disease so as to provide evidence for primary prevention of congenital heart disease.Methods:
Epidemiologic studies on ambient air pollution and congenital heart diseases were reviewed. Summary risk estimates were calculated at high versus low exposure levels and risk per-unit-increase in continuous pollutant concentration. Meta-analysis was conducted with Stata 12.0 software.Results:
A total of 20 articles in English were qualified for inclusion. Results from Meta-analysis showed that CO exposures were related to the increase on the risk of tetralogy of fallot (high versus low exposure level OR=1.22, 95%CI 1.03-1.44), while the exposures to NO(2) were related to the increase on risk of coarctation of aorta (per 10 mm(3)/m(3) OR=1.01, 95%CI 1.01-1.20). Exposures to O(3) were related to the increase on risk of atrial septal defect (per 10 mm(3)/m(3) OR=1.14, 95%CI 1.03-1.26), and PM(10) exposures were related to the increase on risk of atrial septal defect (per 10 µg/m(3) OR=1.10, 95%CI 1.03-1.19). In addition, there were inverse associations between CO and atrial septal defect and between PM(10) and ventricular septal defect.Conclusion:
Exposures to CO, NO(2), O(3), PM(10) during pregnancy seemed to be associated with congenital heart diseases.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Efeitos Tardios da Exposição Pré-Natal
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Poluentes Atmosféricos
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Poluição do Ar
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Cardiopatias Congênitas
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Comunicação Interatrial
Tipo de estudo:
Systematic_reviews
Limite:
Female
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Humans
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Pregnancy
País/Região como assunto:
Asia
Idioma:
Zh
Ano de publicação:
2017
Tipo de documento:
Article