Recurrent bacteremia and liver abscess caused by Clostridium difficile: A case report.
Medicine (Baltimore)
; 96(35): e7969, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28858131
ABSTRACT
RATIONALE Clostridium difficile bacteremia (CDB) and liver abscess is a quite rare presentation of C. difficile infection. PATIENTS CONCERNS A 74-year-old male with primary biliary cirrhosis and hepatocellular carcinoma who underwent transarterial chemoembolization (TACE) developed a high fever on post-TACE day 14. Intravenous ceftriaxone and following meropenem were administered, however, his clinical response was poor. On post-TACE day 24, 2 sets of blood culture were taken due to elevation of C-reactive protein levels. DIAGNOSIS CDB, caused by bacterial translocation. INTERVENTIONS:
Intravenous vancomycin and oral metronidazole were administered for two weeks.OUTCOMES:
One month after recurrent CDB, the patient was re-admitted due to a liver abscess at the same site of TACE. C. difficile was isolated from the liver abscess and the patient received 6 weeks of oral metronidazole treatment. CDB and liver abscess have not recurred since completion of antibiotic treatment. LESSONS The spore-forming ability of C. difficile may contributed to the recurrent CDB episodes and liver abscess formation in necrotic liver tissue following TACE, and long-term metronidazole therapy was considered to be effective to C. difficile liver abscess.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Clostridioides difficile
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Bacteriemia
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Infecções por Clostridium
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Translocação Bacteriana
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Abscesso Hepático
Limite:
Aged
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Humans
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Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article