A Novel Workflow to Enrich and Isolate Patient-Matched EpCAM<sup>high</sup> and EpCAM<sup>low/negative</sup> CTCs Enables the Comparative Characterization of the PIK3CA Status in Metastatic Breast Cancer.

Lampignano, Rita; Yang, Liwen; Neumann, Martin H D; Franken, André; Fehm, Tanja; Niederacher, Dieter; Neubauer, Hans

A Novel Workflow to Enrich and Isolate Patient-Matched EpCAM^high and EpCAM^low/negative CTCs Enables the Comparative Characterization of the PIK3CA Status in Metastatic Breast Cancer.

Lampignano, Rita; Yang, Liwen; Neumann, Martin H D; Franken, André; Fehm, Tanja; Niederacher, Dieter; Neubauer, Hans.

Afiliação

Lampignano R; Department of Obstetrics and Gynecology, Heinrich Heine University of Duesseldorf, Life Science Center, Merowingerplatz 1A, Moorenstr. 5, 40225 Duesseldorf, Germany. rita.lampignano@med.uni-duesseldorf.de.
Yang L; Department of Obstetrics and Gynecology, Heinrich Heine University of Duesseldorf, Life Science Center, Merowingerplatz 1A, Moorenstr. 5, 40225 Duesseldorf, Germany. liwen.yang@med.uni-duesseldorf.de.
Neumann MHD; Department of Obstetrics and Gynecology, Heinrich Heine University of Duesseldorf, Life Science Center, Merowingerplatz 1A, Moorenstr. 5, 40225 Duesseldorf, Germany. neumannmartin1987@gmail.com.
Franken A; Department of Obstetrics and Gynecology, Heinrich Heine University of Duesseldorf, Life Science Center, Merowingerplatz 1A, Moorenstr. 5, 40225 Duesseldorf, Germany. andre.franken@med.uni-duesseldorf.de.
Fehm T; Department of Obstetrics and Gynecology, Heinrich Heine University of Duesseldorf, Life Science Center, Merowingerplatz 1A, Moorenstr. 5, 40225 Duesseldorf, Germany. Tanja.Fehm@med.uni-duesseldorf.de.
Niederacher D; Department of Obstetrics and Gynecology, Heinrich Heine University of Duesseldorf, Life Science Center, Merowingerplatz 1A, Moorenstr. 5, 40225 Duesseldorf, Germany. Niederac@med.uni-duesseldorf.de.
Neubauer H; Department of Obstetrics and Gynecology, Heinrich Heine University of Duesseldorf, Life Science Center, Merowingerplatz 1A, Moorenstr. 5, 40225 Duesseldorf, Germany. Hans.Neubauer@med.uni-duesseldorf.de.

Int J Mol Sci ; 18(9)2017 Aug 31.

Article em En | MEDLINE | ID: mdl-28858218

Assuntos

Neoplasias da Mama; Classe I de Fosfatidilinositol 3-Quinases/sangue; Molécula de Adesão da Célula Epitelial/sangue; Citometria de Fluxo/métodos; Mutação; Proteínas de Neoplasias; Células Neoplásicas Circulantes/metabolismo; Fluxo de Trabalho; Neoplasias da Mama/sangue; Neoplasias da Mama/genética; Feminino; Humanos; Células MCF-7; Proteínas de Neoplasias/sangue; Proteínas de Neoplasias/genética

Palavras-chave

CellCelector; CellSearch; Parsortix; circulating tumor cell; epithelial cell adhesion moleculeow/negative; phosphatidylinositol 3-kinase catalytic subunit alpha

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Fluxo de Trabalho / Classe I de Fosfatidilinositol 3-Quinases / Citometria de Fluxo / Molécula de Adesão da Célula Epitelial / Mutação / Células Neoplásicas Circulantes / Proteínas de Neoplasias Limite: Female / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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