Targeting Type IV Secretion System Proteins to Combat Multidrug-Resistant Gram-positive Pathogens.

Laverde, Diana; Probst, Ines; Romero-Saavedra, Felipe; Kropec, Andrea; Wobser, Dominique; Keller, Walter; Grohmann, Elisabeth; Huebner, Johannes

Laverde, Diana; Probst, Ines; Romero-Saavedra, Felipe; Kropec, Andrea; Wobser, Dominique; Keller, Walter; Grohmann, Elisabeth; Huebner, Johannes.

Afiliação

Laverde D; Division of Pediatric Infectious Diseases, Dr. von Hauner Children's Hospital, Ludwig Maximilians University, Munich.
Probst I; Division of Infectious Diseases, Department of Medicine, University Medical Center Freiburg.
Romero-Saavedra F; Faculty of Biology, Microbiology, Albert Ludwigs University Freiburg.
Kropec A; Division of Pediatric Infectious Diseases, Dr. von Hauner Children's Hospital, Ludwig Maximilians University, Munich.
Wobser D; Division of Infectious Diseases, Department of Medicine, University Medical Center Freiburg.
Keller W; Division of Infectious Diseases, Department of Medicine, University Medical Center Freiburg.
Grohmann E; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Austria.
Huebner J; Division of Infectious Diseases, Department of Medicine, University Medical Center Freiburg.

J Infect Dis ; 215(12): 1836-1845, 2017 06 15.

Article em En | MEDLINE | ID: mdl-28863473

Assuntos

Proteínas de Bactérias/imunologia; Vacinas Bacterianas/imunologia; Farmacorresistência Bacteriana Múltipla/imunologia; Enterococcus faecalis/imunologia; Escherichia coli/imunologia; Sistemas de Secreção Tipo IV/imunologia; Animais; Proteínas de Bactérias/genética; Western Blotting; Enterococcus faecalis/genética; Escherichia coli/genética; Feminino; Fígado/microbiologia; Camundongos; Camundongos Endogâmicos BALB C; Plasmídeos; Transporte Proteico; Coelhos; Staphylococcus aureus/imunologia

Palavras-chave

accine; conjugative transfer; gram-positive pathogens; mouse sepsis model; type IV secretion system (T4SS)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Vacinas Bacterianas / Enterococcus faecalis / Farmacorresistência Bacteriana Múltipla / Escherichia coli / Sistemas de Secreção Tipo IV Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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