Peer victimization predicts heightened inflammatory reactivity to social stress in cognitively vulnerable adolescents.
J Child Psychol Psychiatry
; 59(2): 129-139, 2018 02.
Article
em En
| MEDLINE
| ID: mdl-28892126
ABSTRACT
BACKGROUND:
During adolescence, peer victimization is a potent type of social stressor that can confer enduring risk for poor mental and physical health. Given recent research implicating inflammation in promoting a variety of serious mental and physical health problems, this study examined the role that peer victimization and cognitive vulnerability (i.e. negative cognitive styles and hopelessness) play in shaping adolescents' pro-inflammatory cytokine responses to an acute social stressor.METHODS:
Adolescent girls at risk for psychopathology (n = 157; Mage = 14.73 years; SD = 1.38) were exposed to a laboratory-based social stressor before and after which we assessed salivary levels of three key pro-inflammatory cytokines - interleukin-6 (IL-6), interleukin-1ß (IL-1ß), and tumor necrosis factor-α (TNF-α).RESULTS:
As hypothesized, adolescents with greater peer victimization exposure exhibited greater increases in IL-6 and IL1-ß in response to the laboratory-based social stressor. Moreover, for all three cytokines individually, as well as for a combined latent factor of inflammation, peer victimization predicted enhanced inflammatory responding most strongly for adolescents with high levels of hopelessness.CONCLUSIONS:
The findings reveal a biological pathway by which peer victimization may interact with cognitive vulnerability to influence health in adolescence.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Grupo Associado
/
Estresse Psicológico
/
Citocinas
/
Vítimas de Crime
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Bullying
/
Esperança
/
Inflamação
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
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Female
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Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article