Your browser doesn't support javascript.
loading
Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants.
Alexandru-Crivac, Cristina N; Umeobika, Christian; Leikoski, Niina; Jokela, Jouni; Rickaby, Kirstie A; Grilo, André M; Sjö, Peter; Plowright, Alleyn T; Idress, Mohannad; Siebs, Eike; Nneoyi-Egbe, Ada; Wahlsten, Matti; Sivonen, Kaarina; Jaspars, Marcel; Trembleau, Laurent; Fewer, David P; Houssen, Wael E.
Afiliação
  • Alexandru-Crivac CN; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk and Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
  • Umeobika C; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk.
  • Leikoski N; Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, P.O.Box 56, Biocenter 1, Viikinkaari 9, 00014, Finland. david.fewer@helsinki.fi.
  • Jokela J; Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, P.O.Box 56, Biocenter 1, Viikinkaari 9, 00014, Finland. david.fewer@helsinki.fi.
  • Rickaby KA; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk.
  • Grilo AM; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk and Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
  • Sjö P; Medicinal Chemistry, Respiratory, Inflammation & Autoimmunity, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43183, Sweden.
  • Plowright AT; Medicinal Chemistry, Cardiovascular and Metabolic Diseases Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Pepparedsleden 1, Mölndal, 43183, Sweden.
  • Idress M; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk and Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
  • Siebs E; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk.
  • Nneoyi-Egbe A; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk.
  • Wahlsten M; Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, P.O.Box 56, Biocenter 1, Viikinkaari 9, 00014, Finland. david.fewer@helsinki.fi.
  • Sivonen K; Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, P.O.Box 56, Biocenter 1, Viikinkaari 9, 00014, Finland. david.fewer@helsinki.fi.
  • Jaspars M; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk.
  • Trembleau L; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk.
  • Fewer DP; Microbiology and Biotechnology Division, Department of Food and Environmental Sciences, University of Helsinki, P.O.Box 56, Biocenter 1, Viikinkaari 9, 00014, Finland. david.fewer@helsinki.fi.
  • Houssen WE; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Meston Walk, Aberdeen AB24 3UE, UK. l.trembleau@abdn.ac.uk w.houssen@abdn.ac.uk and Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK and Pharmacognosy Department, Faculty of Pharmacy, Mansoura Un
Chem Commun (Camb) ; 53(77): 10656-10659, 2017 Sep 26.
Article em En | MEDLINE | ID: mdl-28905052
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Compostos Macrocíclicos / Oscillatoria Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Cíclicos / Compostos Macrocíclicos / Oscillatoria Idioma: En Ano de publicação: 2017 Tipo de documento: Article