Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis.

Kwan, Raymond; Brady, Graham F; Brzozowski, Maria; Weerasinghe, Sujith V; Martin, Hope; Park, Min-Jung; Brunt, Makayla J; Menon, Ram K; Tong, Xin; Yin, Lei; Stewart, Colin L; Omary, M Bishr

Kwan, Raymond; Brady, Graham F; Brzozowski, Maria; Weerasinghe, Sujith V; Martin, Hope; Park, Min-Jung; Brunt, Makayla J; Menon, Ram K; Tong, Xin; Yin, Lei; Stewart, Colin L; Omary, M Bishr.

Afiliação

Kwan R; Department of Molecular and Integrative Physiology.
Brady GF; Department of Molecular and Integrative Physiology.
Brzozowski M; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Weerasinghe SV; Department of Molecular and Integrative Physiology.
Martin H; Department of Molecular and Integrative Physiology.
Park MJ; Department of Molecular and Integrative Physiology.
Brunt MJ; Department of Molecular and Integrative Physiology.
Menon RK; Department of Molecular and Integrative Physiology.
Tong X; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Yin L; Department of Molecular and Integrative Physiology.
Stewart CL; Department of Molecular and Integrative Physiology.
Omary MB; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

Cell Mol Gastroenterol Hepatol ; 4(3): 365-383, 2017 Nov.

Article em En | MEDLINE | ID: mdl-28913408

Palavras-chave

% liver weight, liver percentage of body mass; Erk, extracellular signalregulated kinase; FPLD2, Dunnigan familial partial lipodystrophy; Fibrosis; GH, growth hormone; Growth Hormone Signaling; HFD, high-fat diet; Het, heterozygous; Igf1, insulin-like growth factor 1; Jak2, Janus kinase 2; KO, knockout; Laminopathy; Lipodystrophy; NAFLD, nonalcoholic fatty liver disease; ND, normal diet; Nonalcoholic Fatty Liver Disease; PBS, phosphate-buffered saline; Stat, signal transducer and activator of transcription; WT, wild type; qPCR, quantitative polymerase chain reaction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article