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Circulating Normal IgG as Stimulator of Regulatory T Cells: Lessons from Intravenous Immunoglobulin.
Maddur, Mohan S; Kaveri, Srini V; Bayry, Jagadeesh.
Afiliação
  • Maddur MS; Institut National de la Santé et de la Recherche Médicale Unité 1138, Paris, F-75006, France; Centre de Recherche des Cordeliers, Equipe-Immunopathologie et Immunointervention Thérapeutique, Paris, F-75006, France; Sorbonne Universités, UPMC University Paris 06, UMR S 1138, Paris, F-75006, France; Present Address: Pfizer Inc, Pearl River, NY, USA.
  • Kaveri SV; Institut National de la Santé et de la Recherche Médicale Unité 1138, Paris, F-75006, France; Centre de Recherche des Cordeliers, Equipe-Immunopathologie et Immunointervention Thérapeutique, Paris, F-75006, France; Sorbonne Universités, UPMC University Paris 06, UMR S 1138, Paris, F-75006, France; Université Paris Descartes, Sorbonne Paris Cité, UMR S 1138, Paris, F-75006, France.
  • Bayry J; Institut National de la Santé et de la Recherche Médicale Unité 1138, Paris, F-75006, France; Centre de Recherche des Cordeliers, Equipe-Immunopathologie et Immunointervention Thérapeutique, Paris, F-75006, France; Sorbonne Universités, UPMC University Paris 06, UMR S 1138, Paris, F-75006, France; Université Paris Descartes, Sorbonne Paris Cité, UMR S 1138, Paris, F-75006, France. Electronic address: jagadeesh.bayry@crc.jussieu.fr.
Trends Immunol ; 38(11): 789-792, 2017 11.
Article em En | MEDLINE | ID: mdl-28916232
ABSTRACT
Intravenous immunoglobulin (IVIG), a pooled normal IgG formulation prepared from thousands of healthy donors' plasma, is extensively used for the immunotherapy of autoimmune and inflammatory disorders. Recent reports demonstrate that IVIG exerts anti-inflammatory actions by stimulating the activation and expansion of regulatory T (Treg) cells by multiple mechanisms via antigen-presenting cells (APCs).
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Imunoglobulina G / Imunoglobulinas Intravenosas / Linfócitos T Reguladores Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Imunoglobulina G / Imunoglobulinas Intravenosas / Linfócitos T Reguladores Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article