Visible-light-mediated oxidative demethylation of N6-methyl adenines.
Chem Commun (Camb)
; 53(77): 10734-10737, 2017 Sep 26.
Article
em En
| MEDLINE
| ID: mdl-28920612
ABSTRACT
We report a simple protocol that affords oxidative demethylation of N6-methyl groups in N6-methyl adenines (m6A). The biologically compatible photocatalyst riboflavin prompts a highly selective C-H abstraction from N6-methyl in adenines under the irradiation of a visible blue LED light, affording a novel and highly selective biomimetic demethylation of m6A and related N-methyl adenine analogues.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article