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Cysteine-SILAC Mass Spectrometry Enabling the Identification and Quantitation of Scrambled Interchain Disulfide Bonds: Preservation of Native Heavy-Light Chain Pairing in Bispecific IgGs Generated by Controlled Fab-arm Exchange.
van den Bremer, Ewald T J; Labrijn, Aran F; van den Boogaard, Ramon; Priem, Patrick; Scheffler, Kai; Melis, Joost P M; Schuurman, Janine; Parren, Paul W H I; de Jong, Rob N.
Afiliação
  • van den Bremer ETJ; Genmab , Yalelaan 60, 3584CM, Utrecht, The Netherlands.
  • Labrijn AF; Genmab , Yalelaan 60, 3584CM, Utrecht, The Netherlands.
  • van den Boogaard R; Genmab , Yalelaan 60, 3584CM, Utrecht, The Netherlands.
  • Priem P; Genmab , Yalelaan 60, 3584CM, Utrecht, The Netherlands.
  • Scheffler K; Thermo Fisher Scientific GmbH , Im Steingrund 4-6, 63303, Dreieich, Germany.
  • Melis JPM; Genmab , Yalelaan 60, 3584CM, Utrecht, The Netherlands.
  • Schuurman J; Genmab , Yalelaan 60, 3584CM, Utrecht, The Netherlands.
  • Parren PWHI; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center , Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
  • de Jong RN; Genmab , Yalelaan 60, 3584CM, Utrecht, The Netherlands.
Anal Chem ; 89(20): 10873-10882, 2017 10 17.
Article em En | MEDLINE | ID: mdl-28922593
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Anticorpos Biespecíficos / Cisteína / Dissulfetos / Espectrometria de Massas em Tandem Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Anticorpos Biespecíficos / Cisteína / Dissulfetos / Espectrometria de Massas em Tandem Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article