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Self-replicating RNA vaccine functionality modulated by fine-tuning of polyplex delivery vehicle structure.
Démoulins, Thomas; Ebensen, Thomas; Schulze, Kai; Englezou, Pavlos C; Pelliccia, Maria; Guzmán, Carlos A; Ruggli, Nicolas; McCullough, Kenneth C.
Afiliação
  • Démoulins T; Institute of Virology and Immunology (IVI), Sensemattstrasse 293, CH-3147 Mittelhäusern, Switzerland. Electronic address: thomas.demoulins@ivi.admin.ch.
  • Ebensen T; Helmholtz Centre for Infection Research Braunschweig (HZI), Department of Vaccinology and Applied Microbiology, Braunschweig, Germany.
  • Schulze K; Helmholtz Centre for Infection Research Braunschweig (HZI), Department of Vaccinology and Applied Microbiology, Braunschweig, Germany.
  • Englezou PC; Institute of Virology and Immunology (IVI), Sensemattstrasse 293, CH-3147 Mittelhäusern, Switzerland.
  • Pelliccia M; NorthWest Centre of Advanced Drug Delivery (NoWCADD), Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.
  • Guzmán CA; Helmholtz Centre for Infection Research Braunschweig (HZI), Department of Vaccinology and Applied Microbiology, Braunschweig, Germany.
  • Ruggli N; Institute of Virology and Immunology (IVI), Sensemattstrasse 293, CH-3147 Mittelhäusern, Switzerland.
  • McCullough KC; Institute of Virology and Immunology (IVI), Sensemattstrasse 293, CH-3147 Mittelhäusern, Switzerland.
J Control Release ; 266: 256-271, 2017 Nov 28.
Article em En | MEDLINE | ID: mdl-28935594
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoimina / RNA / Vacinas Sintéticas Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoimina / RNA / Vacinas Sintéticas Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article