[Chemical constituents from ripe fruit of Cornus officinalis].
Zhongguo Zhong Yao Za Zhi
; 41(24): 4605-4609, 2016 Dec.
Article
em Zh
| MEDLINE
| ID: mdl-28936844
ABSTRACT
To investigate the chemical compounds from the fruit of Cornus officinalis, six compounds were isolated and determined by extensive spectroscopic analysis as 6'-O-acetyl-7α-O-ethyl morroniside (1), (-)-isolariciresinol 3α-O-ß-D-glucopyranoside(2), apigenin (3), cirsiumaldehyde(4), p-coumaric acid (5), caffeic acid (6). Compound 1 was a new iridoid glucoside,and compounds 2-4 were obtained from the Cornus genus for the first time. Compounds 2-6 were evaluated for the viability of PC12 cells when exposed in conditions of oxygen and glucose deprivation. The MTT results showed that compound 4 increased cell viability moderately in OGD/R treated PC12 cells at the concentration of 1.0 µmolâ¢L⻹.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
/
Cornus
/
Compostos Fitoquímicos
/
Frutas
Limite:
Animals
Idioma:
Zh
Ano de publicação:
2016
Tipo de documento:
Article