Dicipivirus (family Picornaviridae) in wild Northern white-breasted hedgehog (Erinaceus roumanicus).
Arch Virol
; 163(1): 175-181, 2018 Jan.
Article
em En
| MEDLINE
| ID: mdl-28940090
ABSTRACT
Using random amplification and high-throughput sequencing technology a novel picornavirus with dicistronic genome organization and genetically related to canine picodicistrovirus (genus Dicipivirus, family Picornaviridae) was identified and characterized in Northern white-breasted hedgehogs. Hedgehog dicipivirus (hedgehog/H14/2015/HUN, MF188967) was detected in 15 (75%) of 20 faecal specimens by RT-PCR with high viral loads (up to 8.2x108 genomic copies/ml faeces). Hedgehog dicipivirus RNA was also identified in blood, ear skin, abdominal muscle and liver tissues. While the general dicistronic genome organization of hedgehog/H14/2015/HUN is similar to canine picodicistrovirus (5'UTR-P1-IGR-P2/P3-3UTR) there are some unique genome characteristics within the untranslated regions, especially in the functional IRES elements. This study reports the putative second member of the genus Dicipivirus, in a novel host species.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Picornaviridae
/
Infecções por Picornaviridae
/
Ouriços
Tipo de estudo:
Prognostic_studies
Limite:
Animals
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article