Gene-environment interaction between an IL4R variant and school endotoxin exposure contributes to asthma symptoms in inner-city children.

Lai, Peggy S; Massoud, Amir H; Xia, Mingcan; Petty, Carter R; Cunningham, Amparito; Chatila, Talal A; Phipatanakul, Wanda

Lai, Peggy S; Massoud, Amir H; Xia, Mingcan; Petty, Carter R; Cunningham, Amparito; Chatila, Talal A; Phipatanakul, Wanda.

Afiliação

Lai PS; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, Mass; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Mass; Harvard Medical School, Boston, Mass.
Massoud AH; Harvard Medical School, Boston, Mass; Allergy and Immunology, Boston Children's Hospital, Boston, Mass.
Xia M; Harvard Medical School, Boston, Mass; Allergy and Immunology, Boston Children's Hospital, Boston, Mass.
Petty CR; Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Mass.
Cunningham A; Harvard Medical School, Boston, Mass.
Chatila TA; Harvard Medical School, Boston, Mass; Allergy and Immunology, Boston Children's Hospital, Boston, Mass.
Phipatanakul W; Harvard Medical School, Boston, Mass; Allergy and Immunology, Boston Children's Hospital, Boston, Mass. Electronic address: wanda.phipatanakul@childrens.harvard.edu.

J Allergy Clin Immunol ; 141(2): 794-796.e3, 2018 02.

Article em En | MEDLINE | ID: mdl-28943468

Assuntos

Asma; Endotoxinas/toxicidade; Exposição Ambiental; Interação Gene-Ambiente; Polimorfismo Genético; Instituições Acadêmicas; População Urbana; Asma/epidemiologia; Asma/genética; Asma/imunologia; Criança; Feminino; Humanos; Subunidade alfa de Receptor de Interleucina-4/genética; Subunidade alfa de Receptor de Interleucina-4/imunologia; Masculino; Estudos Prospectivos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Asma / Instituições Acadêmicas / População Urbana / Endotoxinas / Exposição Ambiental / Interação Gene-Ambiente Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Child / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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