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Design of Selective Benzoxazepin PI3Kδ Inhibitors Through Control of Dihedral Angles.
Safina, Brian S; Elliott, Richard L; Forrest, Andrew K; Heald, Robert A; Murray, Jeremy M; Nonomiya, Jim; Pang, Jodie; Salphati, Laurent; Seward, Eileen M; Staben, Steven T; Ultsch, Mark; Wei, Binqing; Yang, Wenqian; Sutherlin, Daniel P.
Afiliação
  • Safina BS; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Elliott RL; Discovery from Charles River, 8-9 Spire Green Centre, Harlow, Essex CM 19 5TR, United Kingdom.
  • Forrest AK; Discovery from Charles River, 8-9 Spire Green Centre, Harlow, Essex CM 19 5TR, United Kingdom.
  • Heald RA; Discovery from Charles River, 8-9 Spire Green Centre, Harlow, Essex CM 19 5TR, United Kingdom.
  • Murray JM; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Nonomiya J; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Pang J; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Salphati L; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Seward EM; Discovery from Charles River, 8-9 Spire Green Centre, Harlow, Essex CM 19 5TR, United Kingdom.
  • Staben ST; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Ultsch M; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Wei B; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
  • Yang W; ChemPartner, 998 Halei Road, Zhangjiang Hi-tech Park, Pudong New Area, Shanghai 201203, China.
  • Sutherlin DP; Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
ACS Med Chem Lett ; 8(9): 936-940, 2017 Sep 14.
Article em En | MEDLINE | ID: mdl-28947940
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article