Evidence against a tumour-specific EcoRI RFLP of the c-mos locus.
FEBS Lett
; 230(1-2): 81-4, 1988 Mar 28.
Article
em En
| MEDLINE
| ID: mdl-2895024
ABSTRACT
EcoRI restriction fragment length polymorphisms (RFLP) at the human c-mos locus were analysed in DNAs of normal individuals and tumour patients. Two alleles with fragment lengths of 2.6 kb (A1) and 5.6 kb (A2) respectively were detected. The allele distribution among the tumour group was similar to that of the control group. No difference was found between the allele frequencies in leucocytes and tumour tissue DNA of the same patients.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polimorfismo Genético
/
Polimorfismo de Fragmento de Restrição
/
Proto-Oncogenes
/
DNA
/
Enzimas de Restrição do DNA
/
Neoplasias
Limite:
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article