MWASTools: an R/bioconductor package for metabolome-wide association studies.
Bioinformatics
; 34(5): 890-892, 2018 03 01.
Article
em En
| MEDLINE
| ID: mdl-28961702
ABSTRACT
Summary:
MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of metabolome-wide association studies results. Availability and implementation The MWASTools R package is implemented in R (version > =3.4) and is available from Bioconductor https//bioconductor.org/packages/MWASTools/. Contact m.dumas@imperial.ac.uk. Supplementary information Supplementary data are available at Bioinformatics online.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Metaboloma
/
Metabolômica
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article