Two new 2-(2-Hydroxy-2-phenylethyl)chromens from agarwood originating from Aquilaria crassna.
J Asian Nat Prod Res
; 20(2): 122-127, 2018 Feb.
Article
em En
| MEDLINE
| ID: mdl-28984476
ABSTRACT
Two new 2-(2-hydroxy-2-phenylethyl)chromones (1â2), along with three known 2-(2-phenylethyl)chromones (3â5), were isolated from the agarwood originating from Aquilaria crassna Pierre ex Lecomte. Their structures were determined by the spectroscopic methods including 1D and 2D NMR analysis and comparison with reported data in the literature. All the compounds were isolated from agarwood of A. crassna for the first time. Compounds 1 and 2 exhibited inhibitory activity against acetylcholinesterase (AChE) with 17.4 ± 0.6 and 15.8 ± 0.7%, respectively, at a concentration of 50 µg/ml. Besides, Compound 3 expressed antibacterial activities against Ralstonia solanacearum with diameter of the inhibition zone of 6.80 ± 0.08 mm at a concentration of 10 mg/ml.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Benzopiranos
/
Medicamentos de Ervas Chinesas
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Inibidores da Colinesterase
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Thymelaeaceae
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article