Genetic Control of Lyme Arthritis by <i>Borrelia burgdorferi</i> Arthritis-Associated Locus 1 Is Dependent on Localized Differential Production of IFN-ß and Requires Upregulation of Myostatin.

Paquette, Jackie K; Ma, Ying; Fisher, Colleen; Li, Jinze; Lee, Sang Beum; Zachary, James F; Kim, Yong Soo; Teuscher, Cory; Weis, Janis J

Genetic Control of Lyme Arthritis by Borrelia burgdorferi Arthritis-Associated Locus 1 Is Dependent on Localized Differential Production of IFN-ß and Requires Upregulation of Myostatin.

Paquette, Jackie K; Ma, Ying; Fisher, Colleen; Li, Jinze; Lee, Sang Beum; Zachary, James F; Kim, Yong Soo; Teuscher, Cory; Weis, Janis J.

Afiliação

Paquette JK; Department of Pathology, University of Utah, Salt Lake City, UT 84112.
Ma Y; Department of Pathology, University of Utah, Salt Lake City, UT 84112.
Fisher C; Department of Pathology, University of Utah, Salt Lake City, UT 84112.
Li J; Department of Pathology, University of Utah, Salt Lake City, UT 84112.
Lee SB; Department of Human Nutrition, Food, and Animal Sciences, University of Hawaii at Manoa, Honolulu, HI 96822.
Zachary JF; Department of Veterinary Pathobiology, University of Illinois at Urbana-Champaign, Urbana, IL 61820; and.
Kim YS; Department of Human Nutrition, Food, and Animal Sciences, University of Hawaii at Manoa, Honolulu, HI 96822.
Teuscher C; Department of Medicine, University of Vermont, Burlington, VT 05405.
Weis JJ; Department of Pathology, University of Utah, Salt Lake City, UT 84112; janis.weis@path.utah.edu.

J Immunol ; 199(10): 3525-3534, 2017 11 15.

Article em En | MEDLINE | ID: mdl-28986440

Assuntos

Borrelia burgdorferi/imunologia; Inflamação/imunologia; Interferon beta/metabolismo; Doença de Lyme/imunologia; Macrófagos/imunologia; Miostatina/metabolismo; Animais; Células Cultivadas; Regulação da Expressão Gênica; Loci Gênicos/genética; Inflamação/genética; Doença de Lyme/genética; Camundongos; Camundongos Endogâmicos C3H; Camundongos Endogâmicos C57BL; Miostatina/genética; Quimera por Radiação; Regulação para Cima

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Lyme / Interferon beta / Borrelia burgdorferi / Miostatina / Inflamação / Macrófagos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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