CRISPR/Cas9 screening using unique molecular identifiers.

Schmierer, Bernhard; Botla, Sandeep K; Zhang, Jilin; Turunen, Mikko; Kivioja, Teemu; Taipale, Jussi

Schmierer, Bernhard; Botla, Sandeep K; Zhang, Jilin; Turunen, Mikko; Kivioja, Teemu; Taipale, Jussi.

Afiliação

Schmierer B; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Botla SK; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Zhang J; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
Turunen M; Genome-Scale Biology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Kivioja T; Genome-Scale Biology Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Taipale J; Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden jussi.taipale@ki.se.

Mol Syst Biol ; 13(10): 945, 2017 10 09.

Article em En | MEDLINE | ID: mdl-28993443

Assuntos

Técnicas de Inativação de Genes; Biologia de Sistemas/métodos; Sistemas CRISPR-Cas; Linhagem Celular; Biblioteca Gênica; Células HEK293; Humanos

Palavras-chave

CRISPR/Cas; genetic screening; massively parallel lineage tracing; unique molecular identifiers

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biologia de Sistemas / Técnicas de Inativação de Genes Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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