Human herpesvirus 8-unrelated primary effusion lymphoma-like lymphoma following tyrosine kinase inhibitor treatment for chronic myelogenous leukemia.
J Clin Exp Hematop
; 57(2): 69-73, 2017.
Article
em En
| MEDLINE
| ID: mdl-29021516
ABSTRACT
A 69-year-old man was diagnosed with chronic myelogenous leukemia (CML) and treated with dasatinib. After two years on dasatinib, the patient achieved complete molecular response, but dasatinib treatment was discontinued due to exacerbation of pleural effusion. Nilotinib and imatinib were started but stopped due to an increase in pleural effusion. Thoracentesis was performed and he was diagnosed with human herpesvirus 8-unrelated primary effusion lymphoma (PEL)-like lymphoma. Complex chromosomal abnormality, including BCL6 rearrangement, was found on chromosome analysis. To the best of our knowledge, this is the first report of PEL-like lymphoma following tyrosine kinase inhibitor treatment for CML.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leucemia Mielogênica Crônica BCR-ABL Positiva
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Derrame Pleural Maligno
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Segunda Neoplasia Primária
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Infecções por Herpesviridae
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Herpesvirus Humano 8
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Inibidores de Proteínas Quinases
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Linfoma de Efusão Primária
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Dasatinibe
Limite:
Aged
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Humans
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Male
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article