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N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux.
Ranieri, Roberta; Ciaglia, Elena; Amodio, Giuseppina; Picardi, Paola; Proto, Maria Chiara; Gazzerro, Patrizia; Laezza, Chiara; Remondelli, Paolo; Bifulco, Maurizio; Pisanti, Simona.
Afiliação
  • Ranieri R; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
  • Ciaglia E; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
  • Amodio G; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
  • Picardi P; Department of Pharmacy, University of Salerno, Salerno, Italy.
  • Proto MC; Department of Pharmacy, University of Salerno, Salerno, Italy.
  • Gazzerro P; Department of Pharmacy, University of Salerno, Salerno, Italy.
  • Laezza C; Institute of Endocrinology and Experimental Oncology (IEOS), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.
  • Remondelli P; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
  • Bifulco M; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
  • Pisanti S; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Salerno, Italy.
Cell Death Differ ; 25(2): 353-367, 2018 02.
Article em En | MEDLINE | ID: mdl-29027991

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Proteínas rab de Ligação ao GTP / Prenilação / Proteínas Quinases Ativadas por AMP / Isopenteniladenosina / Melanoma / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Proteínas rab de Ligação ao GTP / Prenilação / Proteínas Quinases Ativadas por AMP / Isopenteniladenosina / Melanoma / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article