Immunobiological efficacy and immunotoxicity of novel synthetically prepared fluoroquinolone ethyl 6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylate.

Jantová, Sona; Paulovicová, Ema; Paulovicová, Lucia; Janosková, Michaela; Pánik, Miroslav; Milata, Viktor

Jantová, Sona; Paulovicová, Ema; Paulovicová, Lucia; Janosková, Michaela; Pánik, Miroslav; Milata, Viktor.

Afiliação

Jantová S; Institute of Biochemistry and Microbiology, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic.
Paulovicová E; Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Bratislava, Slovak Republic. Electronic address: ema.paulovicova@savba.sk.
Paulovicová L; Institute of Chemistry, Center for Glycomics, Slovak Academy of Sciences, Bratislava, Slovak Republic.
Janosková M; Institute of Biochemistry and Microbiology, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic.
Pánik M; Institute of Management, Slovak University of Technology, Bratislava, Slovak Republic.
Milata V; Institute of Organic Chemistry, Catalysis and Petrochemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic.

Immunobiology ; 223(1): 81-93, 2018 01.

Article em En | MEDLINE | ID: mdl-29030009

Assuntos

Antineoplásicos/farmacologia; Epiderme/efeitos dos fármacos; Fibroblastos/efeitos dos fármacos; Fatores Imunológicos/farmacologia; Melanoma/tratamento farmacológico; Quinolinas/farmacologia; Quinolonas/farmacologia; Neoplasias do Colo do Útero/tratamento farmacológico; Animais; Antineoplásicos/síntese química; Apoptose/efeitos dos fármacos; Caspase 9/metabolismo; Processos de Crescimento Celular/efeitos dos fármacos; Sobrevivência Celular; Citocinas/metabolismo; Epiderme/patologia; Feminino; Fibroblastos/patologia; Fluoroquinolonas/química; Células HL-60; Células HeLa; Humanos; Fatores Imunológicos/síntese química; Melanoma/patologia; Melanoma Experimental; Camundongos; Células NIH 3T3; Quinolinas/síntese química; Quinolonas/síntese química; Células RAW 264.7; Neoplasias do Colo do Útero/patologia

Palavras-chave

Anticancer; Cytokines; Cytotoxicity; EpiDerm toxicity; Quinolones

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinolinas / Neoplasias do Colo do Útero / Quinolonas / Epiderme / Fibroblastos / Fatores Imunológicos / Melanoma / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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