Report of a Novel Case of Anaplastic Olfactory Groove Meningioma and Its Methylation Subtype.
J Neuropathol Exp Neurol
; 76(12): 997-999, 2017 Dec 01.
Article
em En
| MEDLINE
| ID: mdl-29045680
ABSTRACT
We report a novel case of a World Health Organization grade 3 anaplastic meningioma arising from the olfactory groove in an 83-year-old woman. Molecular and methylation profiling confirm this lesion to be an NF2 subtype, methylation class intermediate type B meningioma. As most meningiomas in this location are indolent SMO subtype lesions, our report suggests that even though rare, aggressive NF2 subtype meningiomas can also occur along the midline anterior skull base.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Metilação de DNA
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Neoplasias Meníngeas
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Meningioma
Limite:
Aged80
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Female
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Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article