Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease.

Ayton, Scott; James, Simon A; Bush, Ashley I

Ayton, Scott; James, Simon A; Bush, Ashley I.

Afiliação

Ayton S; Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.
James SA; Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia.
Bush AI; Melbourne Dementia Research Centre, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, Australia. Electronic address: ashley.bush@florey.edu.au.

Cell Chem Biol ; 24(10): 1192-1194, 2017 Oct 19.

Article em En | MEDLINE | ID: mdl-29053948

ABSTRACT

ABSTRACT

In this issue of Cell Chemical Biology, Telling et al. (2017) apply advanced X-ray microscopy techniques to reveal magnetite iron species in plaques from a mouse model of Alzheimer's disease. The characterization of abnormal iron chemistry in the disease model highlights the potential for iron to combine with the ß-amyloid peptide and accelerate the disease process.

Assuntos

Doença de Alzheimer/diagnóstico por imagem; Doença de Alzheimer/metabolismo; Ferro/metabolismo; Imagem Molecular; Nanotecnologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanotecnologia / Imagem Molecular / Doença de Alzheimer / Ferro Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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