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6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis.
Tong, Amy S T; Choi, Peter J; Blaser, Adrian; Sutherland, Hamish S; Tsang, Sophia K Y; Guillemont, Jerome; Motte, Magali; Cooper, Christopher B; Andries, Koen; Van den Broeck, Walter; Franzblau, Scott G; Upton, Anna M; Denny, William A; Palmer, Brian D; Conole, Daniel.
Afiliação
  • Tong AST; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Choi PJ; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Blaser A; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Sutherland HS; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Tsang SKY; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Guillemont J; Medicinal Chemistry Department (Infectious Diseases), Janssen Pharmaceuticals, Campus de Maigremont, BP315, 27106 Val de Reuil Cedex, France.
  • Motte M; Medicinal Chemistry Department (Infectious Diseases), Janssen Pharmaceuticals, Campus de Maigremont, BP315, 27106 Val de Reuil Cedex, France.
  • Cooper CB; Global Alliance for TB Drug Development, 40 Wall Street, New York, New York 10005, United States.
  • Andries K; Infectious Diseases BVBA, Janssen Pharmaceuticals, Beerse, Belgium.
  • Van den Broeck W; Infectious Diseases BVBA, Janssen Pharmaceuticals, Beerse, Belgium.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States.
  • Upton AM; Global Alliance for TB Drug Development, 40 Wall Street, New York, New York 10005, United States.
  • Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Palmer BD; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Conole D; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
ACS Med Chem Lett ; 8(10): 1019-1024, 2017 Oct 12.
Article em En | MEDLINE | ID: mdl-29057044

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article