A pilot study of planar coil based magnetic stimulation using acute hippocampal slice in mice.
Annu Int Conf IEEE Eng Med Biol Soc
; 2017: 1118-1121, 2017 Jul.
Article
em En
| MEDLINE
| ID: mdl-29060071
ABSTRACT
Micromagnetic stimulation using small-sized implantable coils has recently been studied. The main advantage of this method is that it can provide sustainable stimulation performance even if a fibrotic encapsulation layer is formed around the implanted coil by inflammation response, because indirectly induced currents are used to induce neural responses. In previous research, we optimized the geometrical and control parameters used in implantable magnetic stimulation. Based on those results, we fabricated the planar coil and studied the LTP effect in the hippocampal slice by two different magnetic stimulation protocols using the quadripulse stimulation (QPS) pattern. We found that direct magnetic stimulation (DMS) induced insignificant LTP effect and priming magnetic stimulation (PMS) occluded LTP effect after tetanic stimulation, when QPS patterned magnetic stimulation with 1 A current pulse was applied to the planar coil.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Magnetismo
Limite:
Animals
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article