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A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer.
Wainberg, Zev A; Alsina, Maria; Soares, Heloisa P; Braña, Irene; Britten, Carolyn D; Del Conte, Gianluca; Ezeh, Patrick; Houk, Brett; Kern, Kenneth A; Leong, Stephen; Pathan, Nuzhat; Pierce, Kristen J; Siu, Lillian L; Vermette, Jennifer; Tabernero, Josep.
Afiliação
  • Wainberg ZA; David Geffen School of Medicine at UCLA, 2020 Santa Monica Blvd, Suite 600, Los Angeles, CA, 90404, USA. ZWainberg@mednet.ucla.edu.
  • Alsina M; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Vall d'Hebron 119-129, 08035, Barcelona, Spain.
  • Soares HP; Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL, 33612, USA.
  • Braña I; Princess Margaret Cancer Centre, 610 University Avenue, Toronto, M5G 2M9, Canada.
  • Britten CD; Medical University of South Carolina, 39 Sabin St., MSC 635, Charleston, SC, 29425, USA.
  • Del Conte G; IRCCS Ospedale S. Raffaele, via Olgettina 60, 20132, Milan, Italy.
  • Ezeh P; Pfizer Oncology, 300 Technology Square, Cambridge, MA, 02139, USA.
  • Houk B; Pfizer Oncology, 10646 Science Center Drive, San Diego, CA, 92121, USA.
  • Kern KA; Pfizer Oncology, 10646 Science Center Drive, San Diego, CA, 92121, USA.
  • Leong S; University of Colorado Denver School of Medicine, 13001 E 17th Place, Aurora, CO, 80045, USA.
  • Pathan N; Pfizer Oncology, 10646 Science Center Drive, San Diego, CA, 92121, USA.
  • Pierce KJ; Pfizer Oncology, 558 Eastern Point Road, Groton, CT, 06340, USA.
  • Siu LL; Princess Margaret Cancer Centre, 610 University Avenue, Toronto, M5G 2M9, Canada.
  • Vermette J; Pfizer Oncology, 300 Technology Square, Cambridge, MA, 02139, USA.
  • Tabernero J; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Vall d'Hebron 119-129, 08035, Barcelona, Spain.
Target Oncol ; 12(6): 775-785, 2017 Dec.
Article em En | MEDLINE | ID: mdl-29067643
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazinas / Benzamidas / Camptotecina / Protocolos de Quimioterapia Combinada Antineoplásica / Morfolinas / Difenilamina / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Neoplasias / Antineoplásicos Fitogênicos Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazinas / Benzamidas / Camptotecina / Protocolos de Quimioterapia Combinada Antineoplásica / Morfolinas / Difenilamina / Serina-Treonina Quinases TOR / Inibidores de Fosfoinositídeo-3 Quinase / Neoplasias / Antineoplásicos Fitogênicos Tipo de estudo: Clinical_trials Limite: Female / Humans / Male Idioma: En Ano de publicação: 2017 Tipo de documento: Article