Synthetic liver function is detectable in transgenic porcine livers perfused with human blood.

Cimeno, Arielle; French, Beth M; Powell, Jessica M; Phelps, Carol; Ayares, David; O'Neill, Natalie A; Laird, Christopher T; Pierson, Richard N; Azimzadeh, Agnes M; Barth, Rolf N; LaMattina, John C

Cimeno, Arielle; French, Beth M; Powell, Jessica M; Phelps, Carol; Ayares, David; O'Neill, Natalie A; Laird, Christopher T; Pierson, Richard N; Azimzadeh, Agnes M; Barth, Rolf N; LaMattina, John C.

Afiliação

Cimeno A; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
French BM; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Powell JM; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Phelps C; Revivicor, Inc., Blacksburg, VA, USA.
Ayares D; Revivicor, Inc., Blacksburg, VA, USA.
O'Neill NA; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Laird CT; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Pierson RN; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Azimzadeh AM; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
Barth RN; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.
LaMattina JC; Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, USA.

Xenotransplantation ; 25(1)2018 01.

Article em En | MEDLINE | ID: mdl-29067741

Assuntos

Sobrevivência de Enxerto/imunologia; Fígado/imunologia; Transplante de Pulmão; Transplante Heterólogo; Animais; Animais Geneticamente Modificados; Antígenos CD55/genética; Circulação Extracorpórea/métodos; Técnicas de Inativação de Genes; Humanos; Fígado/metabolismo; Transplante de Pulmão/métodos; Proteína Cofatora de Membrana/genética; Proteína Cofatora de Membrana/imunologia; Suínos

Palavras-chave

liver xenotransplantation; synthetic function; transgenic pigs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante Heterólogo / Transplante de Pulmão / Sobrevivência de Enxerto / Fígado Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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