Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress.

Jean, Alexandra; Laurent, Laetitia; Delaunay, Sabira; Doly, Stéphane; Dusticier, Nicole; Linden, David; Neve, Rachael; Maroteaux, Luc; Nieoullon, André; Compan, Valérie

Jean, Alexandra; Laurent, Laetitia; Delaunay, Sabira; Doly, Stéphane; Dusticier, Nicole; Linden, David; Neve, Rachael; Maroteaux, Luc; Nieoullon, André; Compan, Valérie.

Afiliação

Jean A; Department of Sciences, Brain, Anorexia & Addiction, Nîmes University, Nîmes 30000, France.
Laurent L; Department of Sciences, Brain, Anorexia & Addiction, Nîmes University, Nîmes 30000, France.
Delaunay S; Department of Sciences, Brain, Anorexia & Addiction, Nîmes University, Nîmes 30000, France.
Doly S; INSERM UMR S839, Paris 75000, France.
Dusticier N; CNRS UMR 7288, Aix-Marseille University, Marseille 13 288, France.
Linden D; Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905, USA.
Neve R; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139-4307, USA.
Maroteaux L; INSERM UMR S839, Paris 75000, France.
Nieoullon A; CNRS UMR 7288, Aix-Marseille University, Marseille 13 288, France.
Compan V; Department of Sciences, Brain, Anorexia & Addiction, Nîmes University, Nîmes 30000, France. Electronic address: valerie.compan@unimes.fr.

Cell Rep ; 21(4): 901-909, 2017 Oct 24.

Article em En | MEDLINE | ID: mdl-29069597

Assuntos

Anorexia/metabolismo; Córtex Pré-Frontal/metabolismo; Núcleos da Rafe/metabolismo; Receptores 5-HT4 de Serotonina/metabolismo; Estresse Psicológico/metabolismo; Adaptação Fisiológica; Animais; Anorexia/etiologia; Anorexia/fisiopatologia; Masculino; Camundongos; Receptores 5-HT4 de Serotonina/genética; Estresse Psicológico/complicações

Palavras-chave

5-HT transporter; 5-HT1A; 5-HT4R; anorexia; appetite; brain; decision; depression; dorsal raphe nucleus; eating; food intake; gene transfer; hypophagia; knockout; medial prefrontal cortex; nucleus accumbens; serotonin; serotonin 4 receptors; siRNA; stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estresse Psicológico / Núcleos da Rafe / Anorexia / Córtex Pré-Frontal / Receptores 5-HT4 de Serotonina Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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