Effects of respiratory muscle training (RMT) in patients with mild to moderate obstructive sleep apnea (OSA).
Sleep Breath
; 22(2): 323-328, 2018 05.
Article
em En
| MEDLINE
| ID: mdl-29080065
ABSTRACT
PURPOSE:
Different forms of training focusing on the muscles of the upper airways showed limited effects on obstructive sleep apnea (OSA) and/or snoring. We investigated the effect of generalized respiratory muscle training (RMT) in lean patients with mild to moderate OSA.METHODS:
Nine male subjects (52.0 ± 10.8 years, BMI 29.1 ± 2.1 kg/m2) with obstructive sleep apnea (apnea-hypopnea index (AHI) 9-29) participated in an open, single-arm pilot study. After a 1-week build-up phase, patients underwent 4 weeks of normocapnic hyperpnea RMT five times a week for 30 min each. The initial and final measurements comprised polysomnography, pulmonary function tests, Epworth sleepiness scale (ESS), and SF-36 questionnaire (quality of life (QoL) self-assessment). The investigational site was a university-affiliated hospital for pulmonary diseases and sleep medicine, Solingen/Germany.RESULTS:
Patients trained effectively, seen by a significant (p < 0.01) increase of breathing frequency (23.3 ± 1.5 /min vs. 30.6 ± 2.9 /min) and minute volume (81.2 ± 13.7 L vs. 109.1 ± 21.9 L). AHI, snoring and ESS remained unchanged after training. QoL as measured by SF-36 significantly (p < 0.05) improved after the training in the subscales "bodily pain" (79 ± 21 vs. 90 ± 12) and "change of health" (3.1 ± 0.3 vs. 2.4 ± 0.5).CONCLUSIONS:
There is no evidence that AHI, pulmonary function or daytime sleepiness are affected by 5 weeks of RMT. Nevertheless, there is an improvement of parameters of quality of life. TRIAL REGISTRATION ClinicalTrials.gov , register no. NCT 00936286.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Exercícios Respiratórios
/
Apneia Obstrutiva do Sono
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article