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Diagnostic Value of Cerebrospinal Fluid T-SPOT.TB for Tuberculousis Meningitis in China.
Li, Xue Lian; Xie, Na; Wang, Song Wang; Wu, Qian Hong; Ma, Yan; Shu, Wei; Chen, Hong Mei; Zhang, Li Qun; Wu, Xiao Guang; Ma, Li Ping; Che, Nan Ying; Gao, Meng Qiu.
Afiliação
  • Li XL; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Xie N; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Wang SW; Public Health Monitor and Information Service Center, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
  • Wu QH; Department of Tuberculosis, Prevention and Treatment Hospital of Shanxi Province, Xian 710100, Shanxi, China.
  • Ma Y; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Shu W; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Chen HM; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Zhang LQ; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Wu XG; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Ma LP; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Che NY; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
  • Gao MQ; Beijing Chest Hospital, Capital Medical University, Beijing 101149, China; Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing 101149, China; Administration Office, Clinical Center on Tuberculosis Control, Chinese Center for Disease Control and Prevention, Beijing 101149, China.
Biomed Environ Sci ; 30(9): 681-684, 2017 Sep.
Article em En | MEDLINE | ID: mdl-29081344
ABSTRACT
The aim of this study was to evaluate the diagnostic value of the cerebrospinal fluid (CSF) T-SPOT.TB test for the diagnosis of TB meningitis (TBM). A retrospective analysis of 96 patients with manifested meningitis was conducted; T-SPOT.TB test was performed for diagnosing TBM to determine the diagnostic sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). A receiver operating characteristic (ROC) curve was also drawn to assess the diagnostic accuracy. The sensitivity, specificity, PPV, and NPV of CSF T-SPOT.TB test were 97.8%, 78.0%, 80.3%, and 97.5%, respectively, for 52 patients (54.2%) of the 96 enrolled patients. The area under the curve (AUC) was 0.910, and the sensitivities of CSF T-SPOT.TB for patients with stages I, II, and III of TBM were 96.7%, 97.2%, and 98.9%, respectively. CSF T-SPOT.TB test is a rapid and accurate diagnostic method with higher sensitivity and specificity for diagnosing TBM.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Meníngea Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose Meníngea Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2017 Tipo de documento: Article