Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.

Ma, D; Chen, X; Zhang, P-Y; Zhang, H; Wei, L-J; Hu, S; Tang, J-Z; Zhou, M-T; Xie, C; Ou, R; Xu, Y; Tang, K-F

Ma, D; Chen, X; Zhang, P-Y; Zhang, H; Wei, L-J; Hu, S; Tang, J-Z; Zhou, M-T; Xie, C; Ou, R; Xu, Y; Tang, K-F.

Afiliação

Ma D; Digestive Cancer Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Chen X; Institute of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Zhang PY; Digestive Cancer Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Zhang H; Institute of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Wei LJ; Digestive Cancer Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Hu S; Institute of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Tang JZ; Digestive Cancer Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Zhou MT; Institute of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Xie C; Digestive Cancer Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Ou R; Institute of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China.
Xu Y; Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, People's Republic of China.
Tang KF; Research Institute of Surgery, Daping Hospital, Third Military Medical University, Chongqing, People's Republic of China.

Oncogene ; 37(8): 1041-1048, 2018 02 22.

Article em En | MEDLINE | ID: mdl-29084207

Assuntos

Carcinoma Hepatocelular/prevenção & controle; Proteína Quinase Ativada por DNA/metabolismo; Dieta/efeitos adversos; Frutose-Bifosfato Aldolase/metabolismo; Regulação Neoplásica da Expressão Gênica; Neoplasias Hepáticas/prevenção & controle; Proteínas Nucleares/metabolismo; Proteína Supressora de Tumor p53/metabolismo; Animais; Apoptose; Biomarcadores Tumorais; Restrição Calórica; Carcinoma Hepatocelular/etiologia; Carcinoma Hepatocelular/metabolismo; Carcinoma Hepatocelular/patologia; Movimento Celular; Proliferação de Células; Proteína Quinase Ativada por DNA/genética; Feminino; Frutose-Bifosfato Aldolase/genética; Humanos; Neoplasias Hepáticas/etiologia; Neoplasias Hepáticas/metabolismo; Neoplasias Hepáticas/patologia; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Invasividade Neoplásica; Proteínas Nucleares/genética; Células Tumorais Cultivadas; Proteína Supressora de Tumor p53/genética; Ensaios Antitumorais Modelo de Xenoenxerto

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Regulação Neoplásica da Expressão Gênica / Proteína Supressora de Tumor p53 / Carcinoma Hepatocelular / Dieta / Proteína Quinase Ativada por DNA / Frutose-Bifosfato Aldolase / Neoplasias Hepáticas Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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