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Gene-Mediated Chemical Communication in Synthetic Protocell Communities.
Tang, T-Y Dora; Cecchi, Dario; Fracasso, Giorgio; Accardi, Davide; Coutable-Pennarun, Angelique; Mansy, Sheref S; Perriman, Adam W; Anderson, J L Ross; Mann, Stephen.
Afiliação
  • Tang TD; Max Planck Institute of Molecular Cell and Genetics , 01307 Dresden, Germany.
  • Cecchi D; BrisSynBio Synthetic Biology Research Centre, Life Sciences Building, University of Bristol , Tyndall Avenue, Bristol BS8 1TQ, U.K.
  • Fracasso G; CIBIO, University of Trento , via Sommarive 9, 38123 Povo, Italy.
  • Accardi D; Max Planck Institute of Molecular Cell and Genetics , 01307 Dresden, Germany.
  • Coutable-Pennarun A; Max Planck Institute of Molecular Cell and Genetics , 01307 Dresden, Germany.
  • Mansy SS; BrisSynBio Synthetic Biology Research Centre, Life Sciences Building, University of Bristol , Tyndall Avenue, Bristol BS8 1TQ, U.K.
  • Perriman AW; CIBIO, University of Trento , via Sommarive 9, 38123 Povo, Italy.
  • Anderson JLR; BrisSynBio Synthetic Biology Research Centre, Life Sciences Building, University of Bristol , Tyndall Avenue, Bristol BS8 1TQ, U.K.
  • Mann S; BrisSynBio Synthetic Biology Research Centre, Life Sciences Building, University of Bristol , Tyndall Avenue, Bristol BS8 1TQ, U.K.
ACS Synth Biol ; 7(2): 339-346, 2018 02 16.
Article em En | MEDLINE | ID: mdl-29091420
ABSTRACT
A gene-directed chemical communication pathway between synthetic protocell signaling transmitters (lipid vesicles) and receivers (proteinosomes) was designed, built and tested using a bottom-up modular approach comprising small molecule transcriptional control, cell-free gene expression, porin-directed efflux, substrate signaling, and enzyme cascade-mediated processing.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Transdução de Sinais / Células Artificiais Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Transdução de Sinais / Células Artificiais Idioma: En Ano de publicação: 2018 Tipo de documento: Article