Characterization of Focal Liver Lesions using CEUS and MRI with Liver-Specific Contrast Media: Experience of a Single Radiologic Center.
Ultraschall Med
; 38(6): 619-625, 2017 Dec.
Article
em En
| MEDLINE
| ID: mdl-29108077
ABSTRACT
AIM:
The purpose of this study was to compare contrast-enhanced ultrasound (CEUS), magnetic resonance imaging (MRI) using liver-specific contrast agent and a combination of both for the characterization of focal liver lesions (FLL).METHODS:
83 patients with both benign and malignant liver lesions were examined using CEUS and MRI after the intravenous administration of liver-specific contrast media. All patients had inconclusive results from prior imaging examinations. Histopathological specimens could be obtained in 53 patients. Ultrasound was performed using a multi-frequency curved probe (1â-â6âMHz) after the injection of 1â-â2.4âml ultrasound contrast media. The sensitivity, specificity, positive predictive value and negative predictive value of CEUS, MRI and a combination of both (CEUS + MRI) were compared.RESULTS:
The sensitivity, specificity, positive and negative predictive values regarding lesion classification were 90.9â%, 70.6â%, 92.3â% and 66.6â%, respectively, for CEUS; 90.9â%, 82.4â%, 95.2â% and 70.0â%, respectively, for MRI; and 96.9â%, 70.6â%, 92.7â% and 85.7â% respectively, for CEUS + MRI. There were no statistically significant differences. 6 malignant lesions were missed using CEUS or MRI alone (false negatives). The use of both modalities combined reduced the false-negative results to 2.CONCLUSION:
CEUS and MRI with liver-specific contrast media are very reliable and of equal informative value in the characterization of focal liver lesions. The number of false-negative results can be decreased using a combination of the two methods.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Hepáticas
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article