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TALENs-mediated homozygous CCR5Δ32 mutations endow CD4+ U87 cells with resistance against HIV­1 infection.
Yu, Ai Qing; Ding, Yan; Lu, Zhi Yong; Hao, Yan Zhe; Teng, Zhi Ping; Yan, Shi Rong; Li, Dong Sheng; Zeng, Yi.
Afiliação
  • Yu AQ; Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
  • Ding Y; Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
  • Lu ZY; Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
  • Hao YZ; State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 100052, P.R. China.
  • Teng ZP; State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 100052, P.R. China.
  • Yan SR; Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
  • Li DS; Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
  • Zeng Y; State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 100052, P.R. China.
Mol Med Rep ; 17(1): 243-249, 2018 Jan.
Article em En | MEDLINE | ID: mdl-29115572
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Infecções por HIV / HIV-1 / Deleção de Sequência / Receptores CCR5 / Resistência à Doença / Nucleases dos Efetores Semelhantes a Ativadores de Transcrição / Homozigoto Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T CD4-Positivos / Infecções por HIV / HIV-1 / Deleção de Sequência / Receptores CCR5 / Resistência à Doença / Nucleases dos Efetores Semelhantes a Ativadores de Transcrição / Homozigoto Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article